HARRISBURG (AP ) – A growing number of unfilled appointments and low uptake among nursing home workers are early signs that vaccine hesitancy is becoming an issue in Pennsylvania. That prompted state officials to sound the alarm and urge residents to get their COVID-19 shots as quickly as possible. After months of demand outstripping supply, vaccines from Pfizer and Moderna are more readily available. The Wolf Administration says the challenge now is to assuage the concerns of people who are reluctant to get the vaccine.